{"id":5735,"date":"2021-06-07T09:44:52","date_gmt":"2021-06-07T08:44:52","guid":{"rendered":"https:\/\/goodgut.eu\/pipeline\/raid-prediction-pipeline\/"},"modified":"2021-07-06T11:35:25","modified_gmt":"2021-07-06T10:35:25","slug":"raid-prediction-pipeline","status":"publish","type":"page","link":"https:\/\/goodgut.eu\/en\/pipeline\/raid-prediction-pipeline\/","title":{"rendered":"RAID-Prediction pipeline"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5735\" class=\"elementor elementor-5735 elementor-2230\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7fddd4e pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7fddd4e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6041a81\" data-id=\"6041a81\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4a6d2fd elementor-widget elementor-widget-text-editor\" data-id=\"4a6d2fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1>RAID-Prediction<\/h1>\n<h3><i>In Vitro<\/i> Diagnostics. Inflammatory Bowel Disease<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-479cb7e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"479cb7e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-29c46c3\" data-id=\"29c46c3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-600f1a1 quadre-pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"600f1a1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-e7366b5\" data-id=\"e7366b5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e07d4f9 elementor-widget elementor-widget-text-editor\" data-id=\"e07d4f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Ideation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-70d389e\" data-id=\"70d389e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3807f58 elementor-widget elementor-widget-text-editor\" data-id=\"3807f58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Definition<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-60fdcfe\" data-id=\"60fdcfe\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-581cd1e elementor-widget elementor-widget-text-editor\" data-id=\"581cd1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Optimitzation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-5e10bff\" data-id=\"5e10bff\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ea9d4dd elementor-widget elementor-widget-text-editor\" data-id=\"ea9d4dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Validation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-c1c8237\" data-id=\"c1c8237\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-774251b elementor-widget elementor-widget-text-editor\" data-id=\"774251b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Regulatory<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-242738f\" data-id=\"242738f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f9c596c elementor-widget elementor-widget-text-editor\" data-id=\"f9c596c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Testing Service<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-317788a\" data-id=\"317788a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d31a63c elementor-widget elementor-widget-text-editor\" data-id=\"d31a63c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Launch<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-ea1fa61\" data-id=\"ea1fa61\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-10a1a3d elementor-widget elementor-widget-text-editor\" data-id=\"10a1a3d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Maintenance<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-f090084 barra-pipeline prediction elementor-widget elementor-widget-global elementor-global-3168 elementor-widget-progress\" data-id=\"f090084\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"progress.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"elementor-progress-wrapper\" role=\"progressbar\" aria-valuemin=\"0\" aria-valuemax=\"100\" aria-valuenow=\"18\">\n\t\t\t<div class=\"elementor-progress-bar\" data-max=\"18\">\n\t\t\t\t<span class=\"elementor-progress-text\"><\/span>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d1755ed pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d1755ed\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e86523f\" data-id=\"e86523f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b12e2e7 elementor-widget elementor-widget-text-editor\" data-id=\"b12e2e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Definition in intestinal biopsies<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1689a7e elementor-widget elementor-widget-image\" data-id=\"1689a7e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_definicion_2.svg\" class=\"attachment-large size-large wp-image-2922\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-06357fc multiply elementor-widget elementor-widget-image\" data-id=\"06357fc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_def.jpg\" class=\"attachment-large size-large wp-image-2938\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_def.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_def-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bb5d670 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"bb5d670\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\"><br>14 patients with CD<br><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a4cfe2d elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"a4cfe2d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\"><br>5 healthy subjects<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d2c168 elementor-widget elementor-widget-spacer\" data-id=\"4d2c168\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-5fd903c\" data-id=\"5fd903c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bca22ae elementor-widget elementor-widget-text-editor\" data-id=\"bca22ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Optimizaation in <br \/>fecal samples<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-26f3a75 elementor-widget elementor-widget-image\" data-id=\"26f3a75\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_optimizacion.svg\" class=\"attachment-large size-large wp-image-2924\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a49a0e multiply elementor-widget elementor-widget-image\" data-id=\"2a49a0e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/testurgut_prediction_opt_logos.jpg\" class=\"attachment-large size-large wp-image-3726\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/testurgut_prediction_opt_logos.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/testurgut_prediction_opt_logos-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d57176f elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"d57176f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\"><br>38 patients with IBD<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a5d5f3 elementor-widget elementor-widget-spacer\" data-id=\"1a5d5f3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d2490a8 pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d2490a8\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d9a1797\" data-id=\"d9a1797\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-19ae718 elementor-widget elementor-widget-text-editor\" data-id=\"19ae718\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"small\">IBS, Irritable Bowel Syndrome; IBD, Inflammatory Bowel Disease<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3805995 elementor-widget elementor-widget-spacer\" data-id=\"3805995\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8ad97a8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8ad97a8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b46f346\" data-id=\"b46f346\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-67ffd8b elementor-widget elementor-widget-text-editor\" data-id=\"67ffd8b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>RAID-Prediction (Risk Assessment of Intestinal Disease &#8211; Prediction) is a non-invasive test that allows to predict treatment response in patients with Crohn&#8217;s disease or Ulcerative Colitis through the determination of a specific microbial signature in feces.<\/h3>\n<h4>Current situation: problems and needs<\/h4>\n<ul>\n<li> Crohn&#8217;s disease and Ulcerative Colitis are chronic inflammatory pathologies that course with alternating periods of activity and remission. The etiology of these pathologies is still unknown, making it difficult to choose the best treatment strategy. <\/li>\n<li> Biologic agents such as the antagonist of tumor necrosis factor alfa (anti-TNF\u03b1) have enabled a substantial advance in the treatment of these patients, improving their quality of life and decreasing surgeries and hospitalizations. <\/li>\n<li> Nevertheless, between 10% and 30% of patients do no respond to initial treatment after the induction period, and 20% to 50% of patients require dose optimization to respond to treatment. <\/li>\n<li> The lack of predictive markers carries unnecessary side effects and a significant economic burden on the public healthcare system. <\/li>\n<li> Personalized medicine can be of great help in the management of IBD, knowing beforehand the most appropriate strategy for each patient. <\/li>\n<\/ul>\n<p><b>There is the need for tools to predict treatment response and offer a personalized strategy.<\/b><\/p>\n<h4>Our proposal<\/h4>\n<p class=\"p1\">RAID-Prediction is a non-invasive system under development that offers to increase the treatment efficacy for patients with Crohn&#8217;s disease or Ulcerative Colitis by determining a specific microbiological signature in fecal samples. The test allows to improve the patient&#8217;s quality of life and reduce substantial associated costs, through the application of personalized medicine.<\/p>\n<p class=\"p3\"> The  <strong> definition <\/strong>of the microbiological signature bases on the study of 19 intestinal biopsies from patients with Crohn&#8217;s disease confirmed with a colonoscopy and healthy subjects, whose comparison in treatment response to Adalimumab &#8211; an anti-TNF\u03b1 &#8211; has allowed identifying a differential signature in responder patients. Identifying these microorganisms in the intestinal mucosa is a key point since it is more stable and resilient against external factors such as diet. The latter allows to avoid variations in the determination and to cover multiple populations with different habits. This first study has been conducted together with the Hospital de Girona Dr. Josep Trueta, the Universitat de Girona and the Institut d\u2019Investigaci\u00f3 Biom\u00e9dica de Girona (IdIBGi). <\/p>\n<p class=\"p3\"> The next step to offer a non-invasive diagnostic test has been to  <strong> optimize <\/strong>the detection in feces of this microbiological signature defined in the intestinal mucosa to predict both treatment response and surgical interventions. To this end, a multicenter observational study has been carried out with a total of 38 fecal samples from subjects with Crohn&#8217;s disease and Ulcerative Colitis, treated with different anti-TNF\u03b1 (Infliximab, Adalimumab, or Golimumab) to differentiate responders from non-responders to the treatment with these agents. National reference hospitals participated: Hospital Universitari de Girona Dr.Josep Trueta, the Hospital Universitari de Bellvitge and the Institut d&#8217;Assist\u00e8ncia Sanit\u00e0ria (IAS). For more information, you can consult the results presented in the XXX Congres of Catalan Society of Digestology 2021  <a href=\"https:\/\/scdigestologia-virtual.cat\/img\/posters\/P71_poster.pdf\" target=\"_blank\" rel=\"noopener\">here. <\/a><\/p>\n<p>Currently, there is ongoing proof-of-concept study that include evaluating specific microbial signatures from responders to other mechanisms of action and treatments. It is performed to include the range of available options and ease the decision-making in managing these patients. Once the definition of all the necessary microbial signatures has been completed and included in the algorithm, validation in an external cohort will follow. It will consist of the same steps as for the development of the other products. With all this, we expect to launch on the market in the following years.<\/p>\n<p>RAID-Prediction will be on the market to predict treatment response in patients with Crohn&#8217;s disease or Ulcerative Colitis. With our research, we want to help in the process to make personalized medicine possible  to improve the quality of life of these patients.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>RAID-Prediction In Vitro Diagnostics. Inflammatory Bowel Disease Ideation Product Definition Product Optimitzation Product Validation Regulatory Testing Service Product Launch Product Maintenance Definition in intestinal biopsies 14 patients with CD 5 healthy subjects Optimizaation in fecal samples 38 patients with IBD IBS, Irritable Bowel Syndrome; IBD, Inflammatory Bowel Disease RAID-Prediction (Risk Assessment of Intestinal Disease &#8211; [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5675,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5735","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5735","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/comments?post=5735"}],"version-history":[{"count":0,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5735\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5675"}],"wp:attachment":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/media?parent=5735"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}