{"id":5733,"date":"2021-06-07T08:55:39","date_gmt":"2021-06-07T07:55:39","guid":{"rendered":"https:\/\/goodgut.eu\/pipeline\/raid-monitor-pipeline\/"},"modified":"2021-07-06T11:30:38","modified_gmt":"2021-07-06T10:30:38","slug":"raid-monitor-pipeline","status":"publish","type":"page","link":"https:\/\/goodgut.eu\/en\/pipeline\/raid-monitor-pipeline\/","title":{"rendered":"RAID-Monitor pipeline"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5733\" class=\"elementor elementor-5733 elementor-2215\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7fddd4e pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7fddd4e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6041a81\" data-id=\"6041a81\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4a6d2fd elementor-widget elementor-widget-text-editor\" data-id=\"4a6d2fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1>RAID-Monitor pipeline<\/h1>\n<h3><em>In vitro<\/em> Diagnostics. Inflammatory Bowel Disease<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-479cb7e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"479cb7e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-29c46c3\" data-id=\"29c46c3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-600f1a1 quadre-pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"600f1a1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-e7366b5\" data-id=\"e7366b5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e07d4f9 elementor-widget elementor-widget-text-editor\" data-id=\"e07d4f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Ideation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-70d389e\" data-id=\"70d389e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3807f58 elementor-widget elementor-widget-text-editor\" data-id=\"3807f58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Definition<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-60fdcfe\" data-id=\"60fdcfe\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-581cd1e elementor-widget elementor-widget-text-editor\" data-id=\"581cd1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Optimitzation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-5e10bff\" data-id=\"5e10bff\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ea9d4dd elementor-widget elementor-widget-text-editor\" data-id=\"ea9d4dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Validation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-c1c8237\" data-id=\"c1c8237\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-774251b elementor-widget elementor-widget-text-editor\" data-id=\"774251b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Regulatory<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-242738f\" data-id=\"242738f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f9c596c elementor-widget elementor-widget-text-editor\" data-id=\"f9c596c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Testing Service<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-317788a\" data-id=\"317788a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d31a63c elementor-widget elementor-widget-text-editor\" data-id=\"d31a63c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Launch<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-ea1fa61\" data-id=\"ea1fa61\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-10a1a3d elementor-widget elementor-widget-text-editor\" data-id=\"10a1a3d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Maintenance<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-4722c3c barra-pipeline monitor elementor-widget elementor-widget-global elementor-global-3056 elementor-widget-progress\" data-id=\"4722c3c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"progress.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"elementor-progress-wrapper\" role=\"progressbar\" aria-valuemin=\"0\" aria-valuemax=\"100\" aria-valuenow=\"30\">\n\t\t\t<div class=\"elementor-progress-bar\" data-max=\"30\">\n\t\t\t\t<span class=\"elementor-progress-text\"><\/span>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d1755ed pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d1755ed\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-e86523f\" data-id=\"e86523f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b12e2e7 elementor-widget elementor-widget-text-editor\" data-id=\"b12e2e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Definition in intestinal biopsies<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1689a7e elementor-widget elementor-widget-image\" data-id=\"1689a7e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_definicion_2.svg\" class=\"attachment-large size-large wp-image-2922\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-06357fc multiply elementor-widget elementor-widget-image\" data-id=\"06357fc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_def.jpg\" class=\"attachment-large size-large wp-image-2938\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_def.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_def-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bb5d670 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"bb5d670\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">45 patients with CD<br>25 patients with UC<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3b346d0 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"3b346d0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">31 healthy subjects<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d2c168 elementor-widget elementor-widget-spacer\" data-id=\"4d2c168\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-470ff9a elementor-widget elementor-widget-button\" data-id=\"470ff9a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26595550\/\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-external-link-alt\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Lopez-Siles M, et al. 2014<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-5fd903c\" data-id=\"5fd903c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bca22ae elementor-widget elementor-widget-text-editor\" data-id=\"bca22ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Optimization in fecal samples<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-26f3a75 elementor-widget elementor-widget-image\" data-id=\"26f3a75\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_optimizacion.svg\" class=\"attachment-large size-large wp-image-2924\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a49a0e multiply elementor-widget elementor-widget-image\" data-id=\"2a49a0e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/testurgut_pipeline_opt_logos.jpg\" class=\"attachment-large size-large wp-image-3520\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/testurgut_pipeline_opt_logos.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/testurgut_pipeline_opt_logos-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d57176f elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"d57176f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">54 patients with CD (34 active and 20 in remission)<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a6ab85c elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"a6ab85c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">79 patients with UC (30 active and 49 in remission)<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a5d5f3 elementor-widget elementor-widget-spacer\" data-id=\"1a5d5f3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-574cca0 elementor-widget elementor-widget-button\" data-id=\"574cca0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/academic.oup.com\/ecco-jcc\/article\/13\/Supplement_1\/S169\/5301259\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-external-link-alt\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Amoedo J, et al. 2019<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-a71dd2c\" data-id=\"a71dd2c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aa95e7a elementor-widget elementor-widget-text-editor\" data-id=\"aa95e7a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Validation in target population<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9d697d2 elementor-widget elementor-widget-image\" data-id=\"9d697d2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_validacion.svg\" class=\"attachment-large size-large wp-image-2926\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4635243 multiply elementor-widget elementor-widget-image\" data-id=\"4635243\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_val-1.jpg\" class=\"attachment-large size-large wp-image-3775\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_val-1.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_monitor_val-1-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-83c4d36 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"83c4d36\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">22 active patients with CD and UC<br><i><b>-<\/b><\/i><b><I>American population-<\/i><\/b><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0219c48 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"0219c48\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">319 patients with CD and UC<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e976259 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"e976259\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/04\/en_curso-1.svg\" class=\"attachment-full size-full wp-image-4950\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">Ongoing Validation<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cb70dea elementor-widget elementor-widget-spacer\" data-id=\"cb70dea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-77f7b58 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"77f7b58\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-35a67af\" data-id=\"35a67af\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4d65377 elementor-widget elementor-widget-text-editor\" data-id=\"4d65377\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"small\" style=\"text-align: center;\">CD, Crohn&#8217;s disease; UC, Ulcerative Colitic<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e3d84ad elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e3d84ad\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-70e7bf0\" data-id=\"70e7bf0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b55fec4 elementor-widget elementor-widget-text-editor\" data-id=\"b55fec4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>RAID-Monitor (Risk Assessment of Intestinal Disease \u2013Monitor) is a non-invasive, comfortable and accurate test for monitoring Crohn&#8217;s disease and Ulcerative Colitis by determining a microbial signature in stools.<\/h3>\n<h4>Current situation: problems and needs<\/h4>\n<ul>\n<li>Inflammatory Bowel Disease (IBD) refers to a group of pathologies that affect the digestive tract, causing inflammatory processes. Crohn&#8217;s disease and Ulcerative Colitis are the most common ones.<\/li>\n<li>Within the last decades, its incidence has been increasing in industrialized countries. It is estimated that affects more than 2.5 million in Europe and 1 million in the United States.<\/li>\n<li>Due to the chronic nature of both conditions and their alternating course with periods of active inflammation and periods of remission, seamless evaluation of the disease is required to adapt the therapeutic strategy and limit its progression and complications.<\/li>\n<li>Colonoscopy is the procedure to follow to precisely check the activity status of the disease, but due to its costs and invasiveness, non-invasive methods are preferred. However, the currently available tests are not sufficiently powerful, so they are used in combination with endoscopic techniques.<\/li>\n<\/ul>\n<p> <strong><i class=\"fas fa-chevron-circle-right\"><\/i> There is the need for non-invasive tests that significantly correlate with the endoscopic activity for the monitoring of IBD. <\/strong><\/p>\n<h4>Our Proposal<\/h4>\n<p>RAID-Monitor is a patented non-invasive system that offers precise monitoring of the activity status of Crohn&#8217;s disease and Ulcerative Colitis by determining a specific microbial signature in the stool sample. The diagnostic capacity of the test is significantly correlated with the endoscopic activity of these patients, offering a more effective alternative than the current available tests and allowing to reduce the number of colonoscopies performed for the monitoring of IBD.<\/p>\n<p class=\"p2\">The <strong>definition <\/strong>of the microbiologic signature bases on the study of 101 intestinal biopsies from patients with IBD and healthy subjects, the comparison of which has enabled the identification of a differential signature in patients with active disease. Identifying these microorganisms in the intestinal mucosa is a key point since it is more stable and resilient against external factors such as diet. The latter allows to avoid variations in the determination and to cover multiple populations with different habits. This first study has been carried out at the Hospital Universitari de Girona Dr. Josep Trueta in collaboration with the Universitat de Girona and the Institut d&#8217;Investigaci\u00f3 Biom\u00e8dica de Girona (IdIBGi).<\/p>\n<p class=\"p2\">The next step to offer a non-invasive test for activity monitoring has been to<b>optimize<\/b>the detection in feces of this microbial signature defined in the intestinal mucosa. For this, a multicenter study has been conducted with a total of 133 fecal samples from patients with Crohn&#8217;s disease and Ulcerative Colitis, knowing their disease status. National reference hospitals participated: Hospital Universitari de Girona Dr.Josep Trueta, the Hospital Universitari de Bellvitge, the Institut d&#8217;Assist\u00e8ncia Sanit\u00e0ria (IAS), and the Hospital Universitari Germans Trias i Pujol. For more information, you can consult the published results from the study here (<a href=\"https:\/\/academic.oup.com\/ecco-jcc\/article\/13\/Supplement_1\/S169\/5301259\" target=\"_blank\" rel=\"noopener\">Amoedo J, et al. 2019<\/a>).<\/p>\n<p class=\"p3\">To <strong>validate <\/strong>that the results from the proof of concept can be extrapolated to other populations with different habits, we conducted a pilot study with 22 American patients from the Beth Israel Deaconess Medical Center in Boston (USA), in which no significant differences were observed in the diagnostic capacity of RAID-Monitor. Moreover, there is an ongoing validation in an external cohort to recruit a minimum of 319 subjects with Crohn&#8217;s Disease and Ulcerative Colitis. The study is conducted in collaboration with the Hospital Universitari de Girona Dr. Josep Trueta, the Institut d\u2019Assist\u00e8ncia Sanit\u00e0ria (IAS), the Hospital Universitari de Bellvitge, the Hospital Universitari Germans Trias I Pujol, and the Hospital General de Granollers.<\/p>\n<p class=\"p1\">RAID-Monitor will be on the market for subjects at legal age diagnosed with Crohn&#8217;s disease or Ulcerative Colitis who want to know the activity status of their disease. With our research, we want to improve the quality of life of patients by offering a fast, comfortable, and precise monitoring of their disease.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>RAID-Monitor pipeline In vitro Diagnostics. Inflammatory Bowel Disease Ideation Product Definition Product Optimitzation Product Validation Regulatory Testing Service Product Launch Product Maintenance Definition in intestinal biopsies 45 patients with CD25 patients with UC 31 healthy subjects Lopez-Siles M, et al. 2014 Optimization in fecal samples 54 patients with CD (34 active and 20 in remission) [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5675,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5733","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/comments?post=5733"}],"version-history":[{"count":0,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5733\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5675"}],"wp:attachment":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/media?parent=5733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}