{"id":5716,"date":"2021-06-04T08:56:33","date_gmt":"2021-06-04T07:56:33","guid":{"rendered":"https:\/\/goodgut.eu\/pipeline\/raid-crc-pipeline\/"},"modified":"2021-07-06T11:33:28","modified_gmt":"2021-07-06T10:33:28","slug":"raid-crc-pipeline","status":"publish","type":"page","link":"https:\/\/goodgut.eu\/en\/pipeline\/raid-crc-pipeline\/","title":{"rendered":"RAID-CRC pipeline"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5716\" class=\"elementor elementor-5716 elementor-1986\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7fddd4e pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7fddd4e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6041a81\" data-id=\"6041a81\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4a6d2fd elementor-widget elementor-widget-text-editor\" data-id=\"4a6d2fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1>RAID-CRC pipeline<\/h1>\n<h3><em>In Vitro<\/em> Diagnostics. Colorrectal cancer<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-479cb7e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"479cb7e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-29c46c3\" data-id=\"29c46c3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-600f1a1 quadre-pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"600f1a1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-e7366b5\" data-id=\"e7366b5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e07d4f9 elementor-widget elementor-widget-text-editor\" data-id=\"e07d4f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Ideation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-70d389e\" data-id=\"70d389e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3807f58 elementor-widget elementor-widget-text-editor\" data-id=\"3807f58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Definition<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-60fdcfe\" data-id=\"60fdcfe\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-581cd1e elementor-widget elementor-widget-text-editor\" data-id=\"581cd1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Optimitzation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-5e10bff\" data-id=\"5e10bff\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ea9d4dd elementor-widget elementor-widget-text-editor\" data-id=\"ea9d4dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Validation<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-c1c8237\" data-id=\"c1c8237\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-774251b elementor-widget elementor-widget-text-editor\" data-id=\"774251b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Regulatory<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-242738f\" data-id=\"242738f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f9c596c elementor-widget elementor-widget-text-editor\" data-id=\"f9c596c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Testing Service<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-317788a\" data-id=\"317788a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d31a63c elementor-widget elementor-widget-text-editor\" data-id=\"d31a63c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Launch<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-12 elementor-inner-column elementor-element elementor-element-ea1fa61\" data-id=\"ea1fa61\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-10a1a3d elementor-widget elementor-widget-text-editor\" data-id=\"10a1a3d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Product Maintenance<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-74db9df barra-pipeline crc elementor-widget elementor-widget-global elementor-global-3062 elementor-widget-progress\" data-id=\"74db9df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"progress.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"elementor-progress-wrapper\" role=\"progressbar\" aria-valuemin=\"0\" aria-valuemax=\"100\" aria-valuenow=\"80\">\n\t\t\t<div class=\"elementor-progress-bar\" data-max=\"80\">\n\t\t\t\t<span class=\"elementor-progress-text\"><\/span>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d1755ed pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d1755ed\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-e86523f\" data-id=\"e86523f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b12e2e7 elementor-widget elementor-widget-text-editor\" data-id=\"b12e2e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Definition in intestinal biopsies<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1689a7e elementor-widget elementor-widget-image\" data-id=\"1689a7e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_definicion_1.svg\" class=\"attachment-large size-large wp-image-2920\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-06357fc multiply elementor-widget elementor-widget-image\" data-id=\"06357fc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_def.jpg\" class=\"attachment-large size-large wp-image-2928\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_def.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_def-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-758784e elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"758784e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">60 patients with CRC<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bb5d670 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"bb5d670\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">20 healthy subjects<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d2c168 elementor-widget elementor-widget-spacer\" data-id=\"4d2c168\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-470ff9a elementor-widget elementor-widget-button\" data-id=\"470ff9a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.tesisenred.net\/handle\/10803\/94513#page=1\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-external-link-alt\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Mas de Xaxars, et al. 2012<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-5fd903c\" data-id=\"5fd903c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bca22ae elementor-widget elementor-widget-text-editor\" data-id=\"bca22ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Optimization in fecal samples<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-26f3a75 elementor-widget elementor-widget-image\" data-id=\"26f3a75\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_optimizacion.svg\" class=\"attachment-large size-large wp-image-2924\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a49a0e multiply elementor-widget elementor-widget-image\" data-id=\"2a49a0e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_opt.jpg\" class=\"attachment-large size-large wp-image-2930\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_opt.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_opt-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d57176f elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"d57176f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">450 subjects with CRC compatible symptomatology<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a6ab85c elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"a6ab85c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">189 subjects from screening population (\u2265 50 years, FIT +, asymptomatic)<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a5d5f3 elementor-widget elementor-widget-spacer\" data-id=\"1a5d5f3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-574cca0 elementor-widget elementor-widget-button\" data-id=\"574cca0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/apt.15251\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-external-link-alt\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Malag\u00f3n M, et al. 2019<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-a71dd2c\" data-id=\"a71dd2c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aa95e7a elementor-widget elementor-widget-text-editor\" data-id=\"aa95e7a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Validation <br \/>in target population<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9d697d2 elementor-widget elementor-widget-image\" data-id=\"9d697d2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/pipeline_validacion.svg\" class=\"attachment-large size-large wp-image-2926\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4635243 multiply elementor-widget elementor-widget-image\" data-id=\"4635243\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"60\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_val.jpg\" class=\"attachment-large size-large wp-image-2932\" alt=\"\" srcset=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_val.jpg 400w, https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/th_logos_crc_val-300x45.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-83c4d36 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"83c4d36\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">327 subjects from screening population (\u2265 50 years, FIT +, asymptomatic)<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0219c48 elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"0219c48\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" src=\"https:\/\/goodgut.eu\/wp-content\/uploads\/2021\/03\/ico-subject.svg\" class=\"attachment-full size-full wp-image-2074\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">2.800 subjects from screening population (\u2265 50 years, FIT +\/-, asymptomatic)<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cb70dea elementor-widget elementor-widget-spacer\" data-id=\"cb70dea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8bfd91 elementor-widget elementor-widget-button\" data-id=\"c8bfd91\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0243158\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-external-link-alt\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Malag\u00f3n M, et al. 2020<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0afbec8 pipeline elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0afbec8\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7cf398d\" data-id=\"7cf398d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d738d8c elementor-widget elementor-widget-text-editor\" data-id=\"d738d8c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"small\">CRC, Colorectal Cancer; FIT, Fecal Immunochemical Test.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cbe1718 elementor-widget elementor-widget-spacer\" data-id=\"cbe1718\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ab537b3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ab537b3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2a7ed1d\" data-id=\"2a7ed1d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a311224 elementor-widget elementor-widget-text-editor\" data-id=\"a311224\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>RAID-CRC (Risk Assessment of Intestinal Disease &#8211; Colorectal Cancer Diagnosis) is a non-invasive, fast, and easy-to-use, and economical test to pre-diagnose colorectal cancer and determine the risk in previous stages using biomarkers present in stool samples<\/h3>\n<h4>Current situation: problems and needs<\/h4>\n<ul>\n<li>Colorectal cancer (CRC) is the third most incident cancer and the second in mortality worldwide, according to the World Health Organization.<\/li>\n<li>European guidelines advise CRC prevention based on population risk detection (people aged from 50 to 75 years)<\/li>\n<li>Current screening programs use the fecal occult blood test (Fecal Immunochemical Test, FIT). However, blood is not a specific marker for CRC, implying a high false-positive rate and a high number of unnecessary colonoscopies.<\/li>\n<\/ul>\n<p><b><i class=\"fas fa-chevron-circle-right\" aria-hidden=\"true\"><\/i> There is the need for non-invasive tools capable of providing early and accurate detection of CRC.<\/b><\/p>\n<h4>Our proposal<\/h4>\n<p>RAID-CRC is a non-invasive patented system that complements the national screening for Colorectal Cancer (CRC) based on the Immunological fecal occult blood test (FIT) by determining a microbiological signature of CRC in the fecal samples. The test presents greater precision for the detection of the precancerous lesion, offering tranquility, comfort, and reduction of unnecessary colonoscopies.<\/p>\n<p>The <strong>definition<\/strong> of the microbiologic signature bases on the study of 80 intestinal biopsies with CRC and subjects with normal colonoscopy, the comparison of which has made it possible to identify a differential signature in patients with the disease. Identifying these bacteria in the intestinal mucosa is a key point, since it is more stable and resilient against external factors such as diet. The latter allows us to avoid variations in determination and to cover different populations with different habits. This first clinical study was carried out at the Hospital Universitari de Girona Dr. Josep Trueta.<\/p>\n<p>The next step to offer a <strong>non-invasive <\/strong>diagnostic test has been to <strong>optimize <\/strong>the detection in feces of the bacterial signature defined in the intestinal mucosa. To this end, a multicenter study was carried out with 450 fecal samples from subjects with CRC compatible symptomatology who underwent a colonoscopy and 189 subjects from a screening population with a positive result in the fecal occult blood test. Five leading hospitals in oncology participated: Hospital Universitari de Girona Dr. Josep Trueta, el Hospital Universitari de Bellvitge, el Institut Catal\u00e0 de Oncologia, el Institut de Salut (IAS), el Consorci Hospitalari de Vic y el Complexo Hospitalario de Ourense. For more information, you can consult the published results of the study here <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/apt.15251\" target=\"_blank\" rel=\"noopener\">(Malag\u00f3n, et al. 2019<\/a> <a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0243158\" target=\"_blank\" rel=\"noopener\">Malag\u00f3n, et al. 2020)<\/a>.<\/p>\n<p>The results of the proof of concept have been <strong>validated <\/strong>in external cohorts with a total of 327 FIT + subjects from the screening population, in collaboration with Hospital Universitari de Girona Dr. Josep Trueta, Hospital Universitari de Bellvitge, and the Institut de Salut (IAS). In addition, to complete the validation of RAID-CRC, a <strong>clinical study <\/strong>has been conducted with 2.800 patients from the German screening program in collaboration with the German Cancer Research Center (DKFZ), a leading European cancer research center. <\/p>\n<p>Currently, RAID-CRC is offered to subjects at legal age with CRC compatible symptomatology or with interest in undergoing a routine control for the early detection of colorectal cancer. With our research we want make available to everyone a precise and comfortable tool for the prevention of this disease.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>RAID-CRC pipeline In Vitro Diagnostics. Colorrectal cancer Ideation Product Definition Product Optimitzation Product Validation Regulatory Testing Service Product Launch Product Maintenance Definition in intestinal biopsies 60 patients with CRC 20 healthy subjects Mas de Xaxars, et al. 2012 Optimization in fecal samples 450 subjects with CRC compatible symptomatology 189 subjects from screening population (\u2265 50 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5675,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5716","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5716","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/comments?post=5716"}],"version-history":[{"count":0,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5716\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/pages\/5675"}],"wp:attachment":[{"href":"https:\/\/goodgut.eu\/en\/wp-json\/wp\/v2\/media?parent=5716"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}